In molecular biology, RNA stability is notoriously difficult to maintain. Unlike DNA, RNA is highly susceptible to degradation — especially by ubiquitous RNases that can ruin precious samples in minutes. For researchers sending RNA for sequencing, qPCR, microarrays, or other downstream applications, ensuring integrity from the bench to the bioinformatics pipeline is critical.
That’s where ITSIprotect-RNA comes in — a powerful, cost-effective solution that protects RNA in both liquid and dry states, outperforming traditional preservation methods like dry ice.
Why RNA Needs Special Protection
RNA’s fragile nature poses challenges at every stage of handling:
- In the lab: RNases exist virtually everywhere — on skin, in dust, on lab surfaces — and even a trace amount can cause rapid degradation.
- During shipment: Fluctuations in temperature and delays in transit increase the risk of breakdown, even when using expensive cold chain logistics.
- In storage: Long-term preservation typically requires ultra-low freezers, which consume significant energy and resources.
For researchers, every lost sample means wasted time, money, and potentially months of experimental work.
The ITSIprotect RNA Solution
ITSIprotect-RNA (Cat No. K-0060) was developed to address these challenges head-on. Using GenTegra Active Chemical Protection™ technology, it forms a protective matrix around RNA molecules the moment it’s added. This matrix prevents enzymatic degradation and environmental damage, keeping your RNA safe in both liquid and dry formats.
Key Benefits at a Glance
- Protection at Every Stage: Safeguards RNA during lab work, shipping, and long-term storage.
- Outperforms Dry Ice: Independent studies have shown better preservation than dry ice shipping.
- Stops RNase Activity Instantly: Begins protecting RNA the moment it’s added.
- Liquid Protection for Days: Keeps RNA intact for up to four days at room temperature.
- Dry Storage for Decades: Near-perfect stability from -80°C to +72°C for years.
- Superior RNAseq Data: Maintains RNA integrity for higher-quality sequencing results.
- Cost Savings: Reduce or eliminate the need for expensive cold chain shipping.
Two Formulations for Maximum Flexibility
To suit different workflows, ITSIprotect-RNA is available in two product variants:
- ITSIprotect-RNA-D (K-0060D): For samples transported and stored dry at room temperature. Ideal for long-term archival and cost-effective shipment without refrigeration.
- ITSIprotect-RNA-L (K-0060L): For samples transported and stored in the liquid state at room temperature. Perfect for short-term handling or when samples will be processed soon after arrival.
Both formats offer the same unmatched protection, long shelf life (>3 years at ambient temperature), and compatibility with all standard buffer systems.
A Better Alternative to RNAstable™
If you’ve used products like RNAstable™ in the past, you’ll find ITSIprotect-RNA to be a perfect — and often superior — replacement. With its advanced chemical protection technology, ITSIprotect-RNA delivers reliable, reproducible results while offering flexibility for both dry and liquid storage conditions.
Environmental & Budget Advantages
By eliminating the need for constant refrigeration or dry ice shipments, ITSIprotect-RNA doesn’t just protect your samples — it protects your budget and the planet. Researchers can reduce packaging waste, lower energy consumption, and avoid the high costs and logistical headaches of cold chain transport.
Applications
ITSIprotect-RNA is ideal for:
- RNA-seq projects
- qPCR workflows
- Microarray analysis
- Clinical and diagnostic research
- Field-based RNA collection
- Archiving precious RNA samples
Whether you’re working in academic research, biotech, clinical diagnostics, or agricultural genomics, ITSIprotect-RNA gives you peace of mind that your samples will arrive and remain exactly as you left them.
Preserve Your RNA with Confidence
RNA degradation doesn’t have to be an inevitable part of molecular biology. With ITSIprotect-RNA, you can ensure that your samples (and your research) remain intact from start to finish.
Shelf Life: >3 years at ambient temperature
To learn more or purchase, visit the ITSIprotect-RNA page or contact our team today.
📧 Contact us: itsi@itsibio.com
📞 Phone: 📱 +1-814-262-7331
🌐 Visit: www.itsibio.com/itsiprotect-rna/
