In the ever-evolving world of life sciences, precision and accuracy are the cornerstones of discovery. From identifying disease biomarkers to developing targeted therapies, researchers need analytical tools that can dive deep into complex biological systems. Tandem Mass Spectrometry (LC-MS/MS) stands at the forefront of these innovations—delivering highly sensitive, specific, and quantitative data that drive meaningful insights.
At ITSI-Biosciences, we specialize in Mass Spectrometry Services that empower scientists to explore the molecular intricacies of their samples with unmatched clarity and confidence.
What Is Tandem Mass Spectrometry (LC-MS/MS)?
Tandem Mass Spectrometry combines liquid chromatography (LC) with mass spectrometry (MS/MS) to separate, identify, and quantify molecules in complex mixtures. The first stage (MS1) measures the mass-to-charge ratios of ions, while the second (MS2) provides detailed fragmentation data—offering a powerful view of molecular structure and abundance.
This dual-stage process makes LC-MS/MS an indispensable tool in modern research, especially for applications in proteomics, metabolomics, and biomarker discovery.
Comprehensive Mass Spec Solutions from ITSI-Biosciences
Our Mass Spectrometry Services are designed to meet the diverse analytical needs of researchers and clinicians. Whether you’re investigating protein function, monitoring metabolic pathways, or searching for diagnostic biomarkers, ITSI-Biosciences delivers the precision and reproducibility your work demands.
Our service offerings include:
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Protein Identification & Characterization
Using nano-LC/MS/MS and advanced database search algorithms, we accurately identify proteins from complex biological samples—whether purified, gel-separated, or digested. -
Quantitative Proteomics (TMT & iTRAQ)
Compare multiple samples in a single experiment with quantitative labeling technologies such as Tandem Mass Tags (TMT). This approach enables robust relative quantification of protein expression across experimental conditions. -
Flash Proteomics Service (FPS)
Need results fast? Our FPS option provides a global protein signature within approximately 48 hours, ideal for time-sensitive projects. -
Metabolomics Profiling
Gain a snapshot of metabolic states with targeted or untargeted metabolomics. Our assays cover primary metabolism, complex lipids, and biogenic amines, supporting biomarker discovery and metabolic research. -
Custom Sample Preparation
From in-gel digestion to biofluid cleanup, our tailored preparation methods ensure reproducible, high-quality data no matter your sample type.
Why Choose ITSI-Biosciences for Mass Spec Analysis?
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State-of-the-art instrumentation: High-resolution LC-MS/MS systems provide unparalleled sensitivity and specificity.
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Experienced scientists: Our team has deep expertise in proteomics, metabolomics, and bioinformatics data analysis.
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Flexible project design: Choose from predefined packages or custom workflows based on your research goals.
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Fast turnaround: Options like our Flash Proteomics Service minimize waiting time without compromising data quality.
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Data you can trust: Every report is quality-checked, annotated, and delivered in publication-ready format.
Applications Across Research & Medicine
Our tandem mass spectrometry workflows support a wide range of applications, including:
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Biomarker discovery and validation
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Drug target identification
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Toxicology and pharmacokinetics
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Food and environmental testing
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Personalized medicine research
By integrating precision analytics with expert interpretation, ITSI-Biosciences helps transform raw data into actionable biological insights.
Partner with Us
Whether you’re a research scientist, biotech innovator, or clinician, ITSI-Biosciences offers the analytical expertise to move your discoveries forward.
Contact us today to discuss your project, request a quote, or learn more about how our Mass Spectrometry Services can advance your research.
📧 itsi@itsibio.com
🌐 itsibio.com/mass-spec-services
📍 Johnstown, PA
