Exploring the Potential of Blood Proteins
Blood is one of the most information-rich biological samples available for biomarker discovery and disease research. It circulates throughout the body, carrying a complex mixture of proteins that reflect physiological and pathological changes. As such, the analysis of blood proteins has become a cornerstone in the search for diagnostic and prognostic biomarkers for diseases such as kidney disorders, urinary tract infections, coronary artery disease, and other systemic conditions.
However, the process of isolating proteins from blood cells can be challenging. Researchers require methods that are not only reproducible and efficient but also compatible with a wide range of downstream analytical platforms.
Introducing the ToPI-Blood Kit (K-0023)
ITSI-Biosciences developed the ToPI-Blood Kit to address these challenges. This validated and optimized solution streamlines the isolation of high-quality proteins from blood cells, enabling accurate and consistent results in proteomic research.
ToPI-Blood provides a simple, reliable workflow for isolating proteins suitable for a variety of downstream applications including:
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Mass spectrometry for quantitative proteomics and biomarker discovery
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Western blotting for protein expression validation
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2D-DIGE for comparative proteomic studies
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SDS-PAGE and other analytical techniques requiring pure, intact protein samples
Ready-to-Use, Optimized Components
Each kit contains everything needed to perform the isolation procedure efficiently and reproducibly:
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10X Buffer – precisely formulated for effective cell lysis and protein solubilization
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Buffer 2 – for optimized protein extraction and stabilization
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Micro grinder pestles and tubes – for effective mechanical disruption of blood cells
These components come pre-measured and ready to use, minimizing preparation time and variability between experiments. This design ensures consistent performance across different users and laboratories.
Why Choose ToPI-Blood?
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Validated and reproducible: Developed and tested by ITSI-Biosciences to ensure consistent protein yield and quality.
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Time-saving: Pre-formulated reagents reduce preparation and optimization steps.
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Versatile: Compatible with a wide range of proteomic and biochemical assays.
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Reliable results: Delivers clean, high-quality protein samples suitable for quantitative and qualitative analyses.
Advancing Blood-Based Biomarker Discovery
As research continues to uncover the diagnostic potential of blood-derived proteins, having a dependable isolation method is essential. The ToPI-Blood Kit empowers researchers to extract high-quality proteins efficiently, laying the foundation for robust data and meaningful discoveries.
Email us at itsi@itsibio.com to learn more or purchase the kit here: https://itsibio.com/product/blood-protein-isolation-kit-topi-blood-k-0023/
